Debbie Crans: Our Fearless Leader
Graduate Student Bios:
Cheryle graduated from Kennesaw State University in Atlanta, Georgia. Her primary research field and expertise are analytical chemistry with a focus in bio-analytical spectroscopic characterization. Her current research includes using fluorescence spectroscopy to characterize inter-peptidic Cu(II) exchange kinetics of some small fluorescent peptide models for amyloid-beta, specifically from Cu-GHW with exchange to GHK/DAHK. This method uses tryptophan fluorescence quenching by paramagnetic Cu(II) to indicate exchange and the manuscript is currently in peer-review. She is currently extending this method to examine the effect of the N-terminus residue on the kinetics of inter-peptidic exchange from Cu-GHW and Cu-GGW complexes to the XAHK motif, where X is a number of different types of residues. She hopes to extend this to the amyloid-beta peptide in the future. She has also looked at metal ion transfer within reverse micelles using a Zn(II) bound photolytic cage and Zincon as an awaiting ligand. Through photolysis using a laser we can break apart the cage and release the metal which can be picked up by the Zincon. This manuscript is currently being written. She was awarded the 2015 Chateaubriand Fellowship to work with Dr. Christelle Hureau in Toulouse, France in 2015, a prominent amyloid researcher and our collaborator on the inter-peptidic Cu(II) exchange kinetics project. Cheryle has also contributed to non-aqueous electrochemistry of menaquinones using cyclic voltammetry for Jordan’s Koehn’s MK project. Personally, Cheryle loves traveling, chemistry, playing World of Warcraft, playing the violin, movies, her kitty Zoe and lounging around the house on weekends with her husband.
Zeyad graduated from the Benghazi University in Libya. He has teaching and research supervision experience in Zoology at Benghazi University and Al-Arab Medical University. Primary research field and expertise is chemical biology with a focus in tuberculosis. His current research includes the examination of how an active tuberculosis drug interacts with model membrane interfaces by using very simple reverse micelle systems to determine exactly how the drug interacts with a membrane. He was also the head of the Biology Department at Faculty of Education in Ghemines/Benghazi University from 2011-13.
Cameron Van Cleave
Heide Murakami graduated with a BS in Chemistry from the University of Hawaii at Manoa. She worked with the UH Cancer Center to develop compounds to use against Glioblastoma. Heide is currently a graduate student in the Crans’ lab at Colorado State University, working as an organic/inorganic chemist. Research interests include organic and inorganic synthesis and medicinal chemistry. If not working, Heide likes to play games, plan D&D campaigns, and read.