I have just upgraded BioWS to WordPress MU 2.8.6 which was released a couple of days ago. The upgrade went smoothly and all sites have had their databases updated. I haven’t found a list of release notes though – probably a lot of security updates.
ALSO – I have upgraded the NextGEN Gallery, Viper’s Video Quicktags, and Contact Form 7 plugins to their most recent releases.
Please let me know if you notice anything goofy! Enjoy!